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RECEPTOR-INTERACTING PROTEIN SERINE-THREONINE KINASES
Descriptors Found:
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DeCS
Descriptor
English
:
Receptor-Interacting Protein Serine-Threonine Kinases
Descriptor
Spanish
:
Proteína Serina-Treonina Quinasas de Interacción con Receptores
Descriptor
Portuguese
:
Proteína Serina-Treonina Quinases de Interação com Receptores
Synonyms
English
:
RIP Serine-Threonine Kinases
Tree Number:
D08.811.913.696.620.682.700.801
D12.644.360.024.296.400
D12.644.360.024.500.186
D12.644.360.075.421.400
D12.776.157.057.024.400
D12.776.157.057.500.186
D12.776.476.024.375.662
D12.776.476.024.500.186
D12.776.476.075.421.400
Definition
English
:
A
family
of serine-threonine kinases that plays a
role
in intracellular
signal transduction
by interacting with a variety of signaling adaptor
proteins
such as
CRADD SIGNALING ADAPTOR PROTEIN
;
TNF RECEPTOR-ASSOCIATED FACTOR 2
; and
TNF RECEPTOR-ASSOCIATED DEATH DOMAIN PROTEIN
. Although they were initially described as
death
domain-binding adaptor
proteins
, members of this
family
may contain other protein-binding domains such as those involving caspase activation and recruitment.
History Note
English
:
2007(1995)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
52250
Unique Identifier:
D053422
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
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